The DeNardo Lab @WUSM

The DeNardo Lab @WUSM The DeNardo Lab @WUSM The DeNardo Lab @WUSM

The DeNardo Lab @WUSM

The DeNardo Lab @WUSM The DeNardo Lab @WUSM The DeNardo Lab @WUSM
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Meet the DeNar-Dawgs

Principal Investigator

David DeNardo, PhD

Graduate Students

Jessica Alexander

Jessica Alexander

Jessica Alexander

PhD Student

MCB Program

alexander.j.m @ wustl.edu

I study Kras and its interaction with the tumor microenviorment.  Outside of the lab I enjoy drawing and painting, listening to music, playing the trumpet, thrifting and antiquing, and trying new things! 

Jie Chen

Jessica Alexander

Jessica Alexander

PhD Student

MGG Program

chen.jie1 @ wustl.edu

I study how to harness radiation therapy (RT)-induced immunogenic cell death to treat PDAC. Outside of the lab, you’ll find me playing the piano, trying new restaurants, playing video and board games, and spending time with my cat. 

Alice Kao

Jessica Alexander

Blake Sells

PhD Student

MGG Program

akao @ wustl.edu

I study immune TMEs across primary and metastatic PDAC, particularly focusing on the macrophage population. Outside of the lab, I like running, hiking and spending time with my cat.

Blake Sells

Jessica Alexander

Blake Sells

MD/PhD Student

Cancer Biology Program

blake.sells @ wustl.edu

 I study how cancer-associated fibrosis and cancer-associated fibroblast phenotypes are modulated in the setting of immunotherapy and the resulting impact this remodeling has in the creation of an effective anti-tumor immune response. Outside of lab, I love to read, try new restaurants, and learn new sports.  

Dev Sen

Alyssa Weinstein

Maddie Turner

PhD Student

MCBProgram

d.sen @ wustl.edu

 I am studying how stromal senescence and metabolic changes influence anti-tumor immune responses and metastasis. Outside of the lab, I enjoy biking, listening to music, and experimenting with new recipes in the kitchen.

Maddie Turner

Alyssa Weinstein

Maddie Turner

MD/PhD Student

Cancer Biology Program

m.c.turner @ wustl.edu

 I am studying how to improve efficacy of radiation therapy in PDAC by combining radiation with other targeted therapies. In my free time I enjoy rock climbing, running in Forest Park, cooking/baking, playing board games, and going to concerts/live music!

Alyssa Weinstein

Alyssa Weinstein

Alyssa Weinstein

PhD Student

Cancer Biology Program

agweinstein @ wustl.edu

 I study dendritic cell differences at the primary and metastatic sites of PDAC. Outside of the lab, you will find me at the CrossFit gym, running around Forest Park, cooking or baking, hiking with my dog, or cuddling on the couch with my cat! 

Faculty & Staff

Brett Knolhoff

Liang-I Kang, MD, PhD

Liang-I Kang, MD, PhD

Lab Manager

bknolhoff @ wustl.edu

I am the lifeblood of this lab, managing the mouse colony as well as everyday operations large and small. Outside of the lab, I enjoy spending time with my wife and two kids. I am an avid sports fan, Go UK Wildcats! In my free time I enjoy playing golf with the guys.

Liang-I Kang, MD, PhD

Liang-I Kang, MD, PhD

Liang-I Kang, MD, PhD

Assistant Professor of Pathology & Immunology 

kangl @ wustl.edu

 I am a board-certified anatomic pathologist. In the DeNardo Lab, I am studying the tumor microenvironment of liver metastases in pancreaticcancer. Outside of lab, I enjoy collecting recipes, reading cookbooks and baking blogs/newsletters, and baking.  

Usman Panni, MD

Liang-I Kang, MD, PhD

Usman Panni, MD

Surgical Oncology Resident

usmanypanni @ wustl.edu

Utilizing novel immunotherapeutic strategies to modulate tumor microenvironment in lung cancer. 


Faiz Ahmad, PhD

Liang-I Kang, MD, PhD

Usman Panni, MD

Staff Scientist

afaiz @ wustl.edu

I conduct clinical biopsies for research, train scientists, design experiments, and analyze data across various projects and collaborations. Outside the lab, I’m passionate about music, books, and nature

Emily Butka, PhD

Emily Butka, PhD

Emily Butka, PhD

Bioinformaticist

ebutka @ wustl.edu

   I lead bioinformatics, data analysis and data management across trainees and projects. In my free time I serve as a bench scientist in my kitchen, trying and testing new and favorite recipes.

Olivia Dres

Emily Butka, PhD

Emily Butka, PhD

Research Technician

d.olivia @ wustl.edu

     To some, I am the mIHC expert; to others, I’m Olivia. I joined the DeNar-Dogs as an American Cancer Society DiCR Intern nearly three years ago and now work full-time. Currently, I work on a myriad of projects, helping others in lab, as well as independent projects. I am currently studying for th

Research Technician

d.olivia @ wustl.edu

     To some, I am the mIHC expert; to others, I’m Olivia. I joined the DeNar-Dogs as an American Cancer Society DiCR Intern nearly three years ago and now work full-time. Currently, I work on a myriad of projects, helping others in lab, as well as independent projects. I am currently studying for the MCAT, as I want to pursue an MD-PhD, but when I have free time, I enjoyed reading, backpacking, and traveling.

Claire Ku

Emily Butka, PhD

Sarah Baek

Undergraduate Research Student

Biology and Anthropology: Global Health and Environment

claireku @ wustl.edu

     I am an undergraduate student at WashU and aspiring future physician. I joined the lab through the American Cancer Society DiCR Program and am currently studying immune profiles of the PDAC TME with my bench mentor, Maddie. In my 

Undergraduate Research Student

Biology and Anthropology: Global Health and Environment

claireku @ wustl.edu

     I am an undergraduate student at WashU and aspiring future physician. I joined the lab through the American Cancer Society DiCR Program and am currently studying immune profiles of the PDAC TME with my bench mentor, Maddie. In my spare time, I love to explore the outdoors, play the piano, and dance.

Sarah Baek

Emily Butka, PhD

Sarah Baek

Undergraduate Student

Biology and Psychological & Brain Sciences

baek.s.s @ wustl.edu

I'm a current undergraduate student at Washington University working part-time to support the gavage team. In my free time, I love drawing, playing the saxophone, and trying new video games.

Lab Alumni

  • John Mitchem, MD (2011-2014; 2016-2018) | Post-doctoral fellow and KL2 mentee. Current: Assistant Professor, Ohio State University.
  • Hong Jiang, MD, PhD (2011-2017) | Post-doctoral fellow. Current: Assistant Professor, Sichuan University.
  • Yu Zhu, PhD (2011-2017) | Graduate student. Current: Instructor of Immunology, Stanford University.
  • Melissa Meyer, PhD (2012-2018) | Graduate student. Current: Assistant Professor, Des Moines University.
  • Samarth Hegde, PhD (2013-2019) | Graduate student. Current: Post-doctoral fellow, Icahn School of Medicine at Mount Sinai.
  • Roheena Panni, MD (2016-2018) | Post-doctoral fellow and surgical resident. Current: Assistant Professor, Washington University in St. Louis.
  • John Baer, PhD (2016-2022) | Graduate student. Current: Research scientist, Canopy Biosciences.
  • Varintra Lander, MD, PhD (2016-2022) | Graduate student (MSTP). Current: Resident in Radiation Oncology (PSTP), Washington University in St. Louis.
  • Jad Belle, MD, PhD (2017-2023) | Graduate student (MSTP). Current: Resident in Dermatology, Stanford University.
  • Natalie Kingston, MD (2018-2021). Current: Resident physician, Yale University.
  • Brett Herzog, MD, PhD (2018-2023) | Post-doctoral fellow and K18 mentee. Current: Assistant Professor, Washington University in St. Louis.
  • Graham Hogg (2018-2024) | Graduate student (MSTP). Current: MD/PhD student in clincal phase.
  • Xiuting Liu, PhD (2018-2025) | Post-doctoral fellow. Current: Professor, China Pharmaceutical University.
  • Alston James, MD (2019-2021) | Resident physician. Current: Surgical fellow, University of Wisconsin.
  • Chong Zou, PhD (2019-2023) | Graduate student. Current: Post-doctoral fellow, Harvard University School of Medicine.
  • Liang-I Kang, MD, PhD (2019-2024) | Post-doctoral fellow and K12 mentee. Current: Assistant Professor of Anatomic and Molecular Pathology, Washington University in St. Louis.
  • Nicholas Borcherding, MD, PhD (2021-2023) | Post-doctoral fellow. Current: Assistant Professor of Pathology and Immunology, Washington University in St. Louis.

Real DeNar-DOGS (And Cats)

Snowball

Snowball

Snowball

Bean

Snowball

Snowball

Cleo

Snowball

Cleo

Hank

Snowball

Cleo

Coconut

Coconut

Coconut

Tanner

Coconut

Coconut

Duke

Coconut

Happy

Happy

Coconut

Happy

Scout

Franklin

Scout

Rosco

Franklin

Scout

Franklin

Franklin

Franklin

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